Release notes Analysis 4.6 (October 29, 2021)

General

The advent of FastFinder Workflow 1.5, FastFinder Analysis 4.6 and Lab management 1.6 brings support for melting curve analyses, a major new capability that allows labs to implement even more of their assay menu on the FastFinder platform. The update also comes with several visualization and usability improvements – such as correcting barcode read errors for sample IDs, and with support added for a number of new cycler instruments.

As always, it is feedback from you that informs our roadmap, and allows us to keep improving FastFinder, so we want to thank you for your continued suggestions. Don’t hesitate to let us know how we can improve FastFinder even further.

For the specific release notes for Lab management 1.6/Workflow 1.5, see (link)

Analysis 4.6.3 (October 29, 2021)

Bug fixes

• When a new version of FastFinder is available, an error message instead of a notification is shown

• Plate tooltip appears multiple times after editing results

• Filename(s) field in Analysis results CSV contains analysis folder name when experiment file was uploaded automatically

Analysis 4.6.1 (October 12, 2021)

New features

With this release, we added support for melting curve analyses, including melting peak visualization that allows you to see the relevant Tm ranges per target with ease, and visualize an in-run quality control of your melt targets. Now, it’s even possible to combine both amplification and melting curve results in the same analysis.

Melting curve analyses are supported for the following instruments:

• BioRad CFX (CFX 96, CFX 384)
• Qiagen Rotor-gene 6000 & Q
• Roche LightCycler 480 Type I & II
• Roche Cobas z480
• ThermoFisher Scientific ViiA7
• ThermoFisher Scientific QuantStudio 3, 5, 5 Dx, 6 Flex, 7 Flex & 12K Flex

And finally, the following newly supported instruments have been added to the FastFinder portfolio:

• ThermoFisher Scientific QuantStudio 6 Flex for both amplification curve and melting curve analyses
• BMG LabTech CLARIOstar Plus, FLUOstar Omega, PHERAstar FSX and POLARstar Omega for endpoint analyses

Improvements

• Automatic plate setup is available for micPCR experiment files if the assay name in the file corresponds to the assay’s Mix instrument reference in FastFinder
• Manual upload of .pcrexperiment and .multiplate files is now possible
• Table sorting and selection of table, graph and plate is remembered when editing results
• To improve the user experience, you can use arrow keys to navigate through plate views and tables
• Easy filtering of all samples having sample comments or previous results in the Sample filter of the Details tab
• In the graph settings, you can configure to visualize positive and negative controls whenever a regular sample is selected. Positive and negative controls are shown respectively in dashed and dotted lines (for amplification and melt analyses), or diamond and cross symbols (for end point analyses)

Fixed bugs

The following issues have been fixed in the Analysis 4.6 release:

• Selection is not remembered in the plate and graph view after editing a result
• Wells in multiplate analyses are not correctly selected when using the CTRL key
• Bulk edit on filtered results not filtered
• Open analyses tab doesn't refresh table when there are no open analyses
• Scrolling issue in Levey-Jennings chart

Design improvements

• Visualization of assay’s and target’s acquisition type
• Improved consistency in labels of buttons shown in dialogs
• Filter button is always shown for tables that have filters
• Improved consistency in table header labels and filters
• Icons are shown in table filters. Options for Today and Last week are added to date filters
• Improved consistency in colors used for statuses
• Table selection via arrow keyboard keys